Medicine

Oncolytic Virus Developed that Targets Cancer Cells and Associated Stromal Cells

Researchers from the University of Oxford and PsiOxus Therapeutics have successfully adapted an oncolytic adenovirus that specifically kills cancer cells, to synthesize a peptide linker that approximates cytotoxic T-cells to cancer-associated fibroblasts in order to eliminate these supportive accomplices. Cancer cells (black) and nearby fibroblasts (red) being killed (green flashes) …

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Compound Found in Congolese Liana Starves Pancreatic Cancer Cells

A team of researchers from Japan, Germany and the Democratic Republic of the Congo has identified an alkaloid compound in a Congolese species of liana that inhibits the survival of pancreatic cancer cells under nutrient-deprived conditions. Ancistrocladus sp. Image credit: Eigenes Werk / CC BY-SA 3.0. Human pancreatic cancer cells …

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Novel Compound Inhibits Inflammation-Triggering Enzyme

An international team of scientists, led by University of Texas and Karolinska Institutet researchers, has created a small anti-inflammatory molecule with a new mechanism of action. Model of TH5487-mediated inhibition of proinflammatory gene expression: inflammation, at its onset and throughout its progress, is associated with generation of reactive oxygen species, …

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Natural Compound Protects Hypertensive Rats against Heart Disease

Low-dose treatment with trimethylamine N-oxide — a compound linked with the consumption of fish, seafood and a primarily vegetarian diet — reduced heart thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension, according to a new study published in the American Journal of Physiology – …

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Blue Light Exposure Reduces Systolic Blood Pressure, Study Shows

Exposure to blue light significantly decreases systolic blood pressure and increases heart rate, lowering the risk of developing cardiovascular disease, a study led by University of Surrey’s Professor Christian Heiss has found. Whole body irradiation with visible blue light improves blood pressure. Image credit: Daniel Reche. “Previous studies have shown …

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