The combination of decaffeinated green tea extract and voluntary exercise can effectively mitigate nonalcoholic fatty liver disease, suggests a new study conducted in mice. Khoo et al investigated the effects of decaffeinated green tea extract, voluntary exercise or the combination on the development of obesity-related nonalcoholic fatty liver disease (NAFLD) …
Read More »Two Glycopeptide Antibiotics Have Never-Before-Seen Way to Kill Bacteria
Two members of a new class of glycopeptide antibiotics — the previously known glycopeptide antibiotic complestatin and a newly-discovered compound called corbomycin — have a unique mechanism of action against bacteria, according to a paper published in the journal Nature. TEM image of Bacillus subtilis grown in corbomycin shows a …
Read More »Immune Cells Congregate and Coordinate with Neighbors to Decide Whether to React: Study
Scientists have long known that immune cells migrate to the site of an infection, which individuals experience as inflammation. Now, a team of researchers at the University of Washington and Northwestern University has uncovered evidence that this gathering is not just a consequence of immune activation; immune cells ‘count’ how …
Read More »Modified Sugars Show Broad-Spectrum Virucidal Activity
A team of researchers from the University of Manchester, the University of Geneva, and the EPFL has synthesized new antiviral materials that proved to be active against a large number of viruses, including herpes simplex virus, respiratory syncytial virus, dengue virus, and Zika virus. Made from cyclodextrins, naturally occurring derivatives …
Read More »Fat Cells Can Sense Light, Animal Study Shows
Light exposure regulates how two kinds of fat cells (adipocytes) work together to produce the raw materials that all other cells use for energy, according to a new study conducted in mice. White fat cells (adipocytes) activate the lipolysis pathway to produce the free fatty acids that are used as …
Read More »Newly-Identified Coronavirus 2019-nCoV: Here’s What You Need to Know
The current outbreak of viral pneumonia in Wuhan, a rapidly flourishing capital city of the Hubei province and the traffic hub of central China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization (WHO). TEM image of 2019-nCoV particles. Image credit: Zhu et al, doi: 10.1056/NEJMoa2001017. …
Read More »Powerful Combination of Two Experimental Drugs Counteracts Osteoarthritis in Rats
A research team headed by scientists at the Salk Institute for Biological Studies has discovered that a combination of two molecules, alpha-KLOTHO (αKLOTHO) and TGF beta receptor 2 (TGFβR2), reverses the cellular and molecular signs of osteoarthritis in rats as well as in isolated human cartilage cells. The top image …
Read More »Scientists Find Cell-Free Mitochondria in Human Blood
Mitochondria are considered as the power-generating units of the cell due to their key role in energy metabolism and intercellular communication. However, cell-derived mitochondrial components could be found in the extracellular space, as fragments or encapsulated in vesicles. Now, a team of researchers has demonstrated that human blood contains whole …
Read More »This Sci-Fi-Inspired Device Could Replace Bulky, Expensive X-Ray Machines
We’re still a long way from Star Trek-style tricorders that can instantly diagnose disease, but medical startup Nanox is hoping to bring a little of the 24th century to a hospital near you. The company has unveiled a new low-cost X-ray scanner called the Nanox.Arc. It hopes to deploy …
Read More »Habitual Tea Drinking Reduces Risk of Cardiovascular Disease
Using large prospective cohorts among Chinese adults, a research team led by the Chinese Academy of Medical Sciences and Peking Union Medical College has provided new evidence on the protective role of tea consumption on atherosclerotic cardiovascular disease events and all-cause mortality, especially among those who kept the habit all …
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